Gel Hydrogels Used as Scaffolding in Construction - 986 Words

Gel hydrogels can be considered as promising materials to be used as scaffold in tissue engineering since they present a load-bearing capacity and suitable mechanical properties.6 Almost all the measurements on the mechanical properties of hydrogel materials have used true stress-true strain or engineering stress-engineering strain definitions on the grounds of hydrogel incompressibility.26 However, there is no agreement as to which stress-strain definition should be adopted to determine the mechanical behavior of hydrogel materials in a compressive testing machine. Hydrogels are known to exhibit elastic behavior,27 hence, the elastic modulus, maximum stress and strain of Gel hydrogels are investigated. The stress-strain definition may substantially affect the measured mechanical properties, including elastic modulus, maximum stress and strain. A Gel hydrogel is illustrated in Figure 1. A cylindrical chamber was used to form a suitable shape for the samples. Samples were set on the l ower plate of the testing machine and compressed by the upper plate which was connected to a load cell until failure. Figure 2 shows various stress-strain curves using four definitions for strain (engineering strain, Green-St. Venant strain, Almansi-Hamel strain, and true strain) and three definitions for stress (second Piola-Kirchhoff stress, engineering stress, and true stress). This figure shows that the way in which stress-strain is defined has a profound effect on the stress-strainShow MoreRelatedA Simplistic, Cost Efficient Method Of Creating Artificial Vascular Structures Essay2063 Words   |  9 Pagesresearch and its use. Currently, a major issue facing the transplanting of vascular systems is the incapability of the recipient’s cells to accept the foreign systems into use. However, this issue is not of concern when Poly(N-isopropylacrylamide) is used as this polymer has the ability to order itself in order to make hydrogen bonds with the water molecules in which it is submerged, once inside the cell. By heating up the polymer it can be determined that the negative entropy dominates due to the temperature